{"id":583,"date":"2023-05-10T15:38:55","date_gmt":"2023-05-10T07:38:55","guid":{"rendered":"https:\/\/nugene.com.cn\/en\/?page_id=583"},"modified":"2023-05-11T09:10:38","modified_gmt":"2023-05-11T01:10:38","slug":"modified-nucleoside","status":"publish","type":"page","link":"https:\/\/nugene.com.cn\/en\/index.php\/modified-nucleoside\/","title":{"rendered":"Modified Nucleoside"},"content":{"rendered":"\n

Fluoro Modified Nucleoside<\/p>\n\n\n\n

Item No.<\/strong><\/td>Short Name<\/strong><\/td>Chemical Name<\/strong><\/td>Formula<\/strong><\/td>Molecular Weight<\/strong><\/td>CAS NO<\/strong><\/td><\/tr>
H105C-00<\/td>2′-F-2′-dA<\/td>2′-Fluoro-2′-Deoxyadenosine<\/td>C10H12FN5O3<\/td>269.24<\/td>64183-27-3<\/td><\/tr>
H205C-00<\/td>2′-F-2′-dC<\/td>2′-Fluoro-2′-Deoxycytidine<\/td>C9H12FN3O4<\/td>245.21<\/td>10212-20-1<\/td><\/tr>
H305C-00<\/td>2′-F-2′-dG<\/td>2′-Fluoro-2′-Deoxyguanosine<\/td>C10H12FN5O4 <\/td>285.23<\/td>78842-13-4<\/td><\/tr>
H405C-00<\/td>2′-F-2′-dU<\/td>2′-Fluoro-2′-Deoxyuridine<\/td>C9H11FN2O5<\/td>246.2<\/td>784-71-4<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

O-Methyl Modified Nucleoside<\/p>\n\n\n\n

Item No.<\/strong><\/td>Chemical Name<\/strong><\/td>Formula<\/strong><\/td>Molecular Weight<\/strong><\/td>CAS NO<\/strong><\/td><\/tr>
H103C-00<\/td>2\u2032-O-Methyladenosine<\/td>C11H15N5O4<\/td>281.27<\/td>2140-79-6<\/td><\/tr>
H203C-00<\/td>2′-O-Methylcytidine<\/td>C10H15N3O5<\/td>257.24<\/td>2140-72-9<\/td><\/tr>
H303C-00<\/td>2′-O-Methylguanosine<\/td>C11H15N5O5<\/td>297.27<\/td>2140-71-8<\/td><\/tr>
H403C-00<\/td>2′-O-Methyluridine<\/td>C10H14N2O6<\/td>258.23<\/td>2140-76-3<\/td><\/tr>
H903C-00<\/td>2′-O-Me-5-Me-Cytidine<\/td>C11H17N3O5<\/td>271.27<\/td>113886-70-7<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

Modified nucleoside refers to a nucleoside molecule that has undergone chemical modifications to its structure. Nucleosides are building blocks of nucleic acids, DNA and RNA, consisting of a nitrogenous base and a five-carbon sugar molecule (ribose or deoxyribose). In modified nucleosides, the nitrogenous base or the sugar has been altered by adding or removing functional groups, which can affect the base pairing and hydrogen bonding properties of the nucleotide. These modified nucleosides can occur naturally in some organisms or can be engineered by synthetic biology techniques. They have various biological functions, such as regulating gene expression, providing chemical stability, or modulating enzymatic activity. Modified nucleosides are being studied for their potential applications in gene therapy, drug development, and synthetic biology.<\/p>\n\n\n\n

Nugene as a part of Zhejiang Hengkang Pharmaceutical, provides modified nucleoside in large-scale, our modified nucleoside is used in CMO\/CDMO industry for phosphoramidite mononer that is key materials for synthesis of Oligonucleotide, such as ASO, siRNA, etc. The high quality help clients to prepare high purity and low mutation ASO and siRNA, accelerate R&D and save cost.<\/p>\n\n\n\n

Packing size:<\/strong> 1kg\/bag, 5kg\/bag, 15kg\/bag.<\/p>\n","protected":false},"excerpt":{"rendered":"

Fluoro Modified Nucleoside Item No. Short Name Chemical Name Formula Molecular Weight CAS NO H105C-00 2′-F-2′-dA 2′-Fluoro-2′-Deoxyadenosine C10H12FN5O3 269.24 64183-27-3 H205C-00 2′-F-2′-dC 2′-Fluoro-2′-Deoxycytidine C9H12FN3O4 245.21 10212-20-1 H305C-00 2′-F-2′-dG 2′-Fluoro-2′-Deoxyguanosine C10H12FN5O4  285.23 78842-13-4 H405C-00 2′-F-2′-dU 2′-Fluoro-2′-Deoxyuridine C9H11FN2O5 246.2 784-71-4 O-Methyl Modified Nucleoside Item No. Chemical Name Formula Molecular Weight CAS NO H103C-00 2\u2032-O-Methyladenosine C11H15N5O4 281.27 2140-79-6 …<\/p>\n

Modified Nucleoside<\/span> Read More »<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"default","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","footnotes":""},"class_list":["post-583","page","type-page","status-publish","hentry"],"yoast_head":"\nModified Nucleoside - Nucleic acid Building Block<\/title>\n<meta name=\"description\" content=\"nugene as part of zhejiang hengkang pharmaceutical provide modified nucleosde, that is used for synthesis of phosphoramidite which is for oligo.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/nugene.com.cn\/en\/index.php\/modified-nucleoside\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Modified Nucleoside - Nucleic acid Building Block\" \/>\n<meta property=\"og:description\" content=\"nugene as part of zhejiang hengkang pharmaceutical provide modified nucleosde, that is used for synthesis of phosphoramidite which is for oligo.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/nugene.com.cn\/en\/index.php\/modified-nucleoside\/\" \/>\n<meta property=\"og:site_name\" content=\"Nucleic acid Building Block\" \/>\n<meta property=\"article:modified_time\" content=\"2023-05-11T01:10:38+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:site\" content=\"@AndyLu_Pharma\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/nugene.com.cn\/en\/index.php\/modified-nucleoside\/\",\"url\":\"https:\/\/nugene.com.cn\/en\/index.php\/modified-nucleoside\/\",\"name\":\"Modified Nucleoside - Nucleic acid Building Block\",\"isPartOf\":{\"@id\":\"http:\/\/nugene.com.cn\/en\/#website\"},\"datePublished\":\"2023-05-10T07:38:55+00:00\",\"dateModified\":\"2023-05-11T01:10:38+00:00\",\"description\":\"nugene as part of zhejiang hengkang pharmaceutical provide modified nucleosde, that is used for synthesis of phosphoramidite which is for oligo.\",\"breadcrumb\":{\"@id\":\"https:\/\/nugene.com.cn\/en\/index.php\/modified-nucleoside\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/nugene.com.cn\/en\/index.php\/modified-nucleoside\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/nugene.com.cn\/en\/index.php\/modified-nucleoside\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"\u9996\u9875\",\"item\":\"http:\/\/nugene.com.cn\/en\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Modified Nucleoside\"}]},{\"@type\":\"WebSite\",\"@id\":\"http:\/\/nugene.com.cn\/en\/#website\",\"url\":\"http:\/\/nugene.com.cn\/en\/\",\"name\":\"Nucleic acid Building Block\",\"description\":\"service@nugene.com.cn; Hangzhou, China\",\"publisher\":{\"@id\":\"http:\/\/nugene.com.cn\/en\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"http:\/\/nugene.com.cn\/en\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"http:\/\/nugene.com.cn\/en\/#organization\",\"name\":\"Nugene Biopharm Science\",\"url\":\"http:\/\/nugene.com.cn\/en\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"http:\/\/nugene.com.cn\/en\/#\/schema\/logo\/image\/\",\"url\":\"http:\/\/nugene.com.cn\/en\/wp-content\/uploads\/2021\/08\/logo-2.png\",\"contentUrl\":\"http:\/\/nugene.com.cn\/en\/wp-content\/uploads\/2021\/08\/logo-2.png\",\"width\":180,\"height\":60,\"caption\":\"Nugene Biopharm Science\"},\"image\":{\"@id\":\"http:\/\/nugene.com.cn\/en\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/twitter.com\/AndyLu_Pharma\",\"https:\/\/www.linkedin.com\/company\/nugene\/?viewAsMember=true\"]}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Modified Nucleoside - Nucleic acid Building Block","description":"nugene as part of zhejiang hengkang pharmaceutical provide modified nucleosde, that is used for synthesis of phosphoramidite which is for oligo.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/nugene.com.cn\/en\/index.php\/modified-nucleoside\/","og_locale":"en_US","og_type":"article","og_title":"Modified Nucleoside - Nucleic acid Building Block","og_description":"nugene as part of zhejiang hengkang pharmaceutical provide modified nucleosde, that is used for synthesis of phosphoramidite which is for oligo.","og_url":"https:\/\/nugene.com.cn\/en\/index.php\/modified-nucleoside\/","og_site_name":"Nucleic acid Building Block","article_modified_time":"2023-05-11T01:10:38+00:00","twitter_card":"summary_large_image","twitter_site":"@AndyLu_Pharma","twitter_misc":{"Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/nugene.com.cn\/en\/index.php\/modified-nucleoside\/","url":"https:\/\/nugene.com.cn\/en\/index.php\/modified-nucleoside\/","name":"Modified Nucleoside - Nucleic acid Building Block","isPartOf":{"@id":"http:\/\/nugene.com.cn\/en\/#website"},"datePublished":"2023-05-10T07:38:55+00:00","dateModified":"2023-05-11T01:10:38+00:00","description":"nugene as part of zhejiang hengkang pharmaceutical provide modified nucleosde, that is used for synthesis of phosphoramidite which is for oligo.","breadcrumb":{"@id":"https:\/\/nugene.com.cn\/en\/index.php\/modified-nucleoside\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/nugene.com.cn\/en\/index.php\/modified-nucleoside\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/nugene.com.cn\/en\/index.php\/modified-nucleoside\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"\u9996\u9875","item":"http:\/\/nugene.com.cn\/en\/"},{"@type":"ListItem","position":2,"name":"Modified Nucleoside"}]},{"@type":"WebSite","@id":"http:\/\/nugene.com.cn\/en\/#website","url":"http:\/\/nugene.com.cn\/en\/","name":"Nucleic acid Building Block","description":"service@nugene.com.cn; Hangzhou, China","publisher":{"@id":"http:\/\/nugene.com.cn\/en\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"http:\/\/nugene.com.cn\/en\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"en-US"},{"@type":"Organization","@id":"http:\/\/nugene.com.cn\/en\/#organization","name":"Nugene Biopharm Science","url":"http:\/\/nugene.com.cn\/en\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"http:\/\/nugene.com.cn\/en\/#\/schema\/logo\/image\/","url":"http:\/\/nugene.com.cn\/en\/wp-content\/uploads\/2021\/08\/logo-2.png","contentUrl":"http:\/\/nugene.com.cn\/en\/wp-content\/uploads\/2021\/08\/logo-2.png","width":180,"height":60,"caption":"Nugene Biopharm Science"},"image":{"@id":"http:\/\/nugene.com.cn\/en\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/twitter.com\/AndyLu_Pharma","https:\/\/www.linkedin.com\/company\/nugene\/?viewAsMember=true"]}]}},"_links":{"self":[{"href":"https:\/\/nugene.com.cn\/en\/index.php\/wp-json\/wp\/v2\/pages\/583","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nugene.com.cn\/en\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/nugene.com.cn\/en\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/nugene.com.cn\/en\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/nugene.com.cn\/en\/index.php\/wp-json\/wp\/v2\/comments?post=583"}],"version-history":[{"count":5,"href":"https:\/\/nugene.com.cn\/en\/index.php\/wp-json\/wp\/v2\/pages\/583\/revisions"}],"predecessor-version":[{"id":606,"href":"https:\/\/nugene.com.cn\/en\/index.php\/wp-json\/wp\/v2\/pages\/583\/revisions\/606"}],"wp:attachment":[{"href":"https:\/\/nugene.com.cn\/en\/index.php\/wp-json\/wp\/v2\/media?parent=583"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}