Oligo

oligonucleotide

Nusinersen sodium

CAS NO.: 1258984-36-9Synonyms: Nusinersen USP/EP/BPMolecular Formula: C234H340N61O128P17S17Molecular Weight:7127.194237 Application: Nusinersen, marketed as Spinraza, is a medication used in treating spinal muscular atrophy (SMA), a rare neuromuscular disorder. In December 2016, it became the first approved drug used in treating this disorder. Any product involved in patent will be used for research purposes only.

Inotersen sodium

CAS NO.: 1432726-13-0Synonyms: ISIS-420915 sodiumMolecular Formula: C230H299N69Na19O121P19S19Molecular Weight:7601 Application: Any product involved in patent will be used for research purposes only.

Volanesorsen

CAS NO.: 915430-78-3 / 1573402-50-22 (sodium salt)Synonyms: ISIS 304801Molecular Formula: C230H320N63O125P19S19Molecular Weight:7165.05 Application: Volanesorsen, sold under the brand name Waylivra, is a triglyceride-reducing drug. It is a second-generation 2′-O-methoxyethyl (2′-MOE) chimeric antisense therapeutic oligonucleotide (ASO) that targets the messenger RNA for apolipoprotein C3 (apo-CIII). Any product involved in patent will be used for research purposes …

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Golodirsen

CAS NO.: 1422959-91-8Synonyms: SRP-4053Molecular Formula: C305H481N138O112P25Molecular Weight:8647.401 Application: Golodirsen, sold under the brand name Vyondys 53, is a medication used for the treatment of Duchenne muscular dystrophy (DMD). It is an antisense oligonucleotide drug of phosphorodiamidate morpholino oligomer (PMO) chemistry. Any product involved in patent will be used for research purposes only.

Casimersen

CAS NO.: 1422958-19-7Synonyms: SRP-4045Molecular Formula: C268H424N124O95P22Molecular Weight:7584.536 Application: Casimersen, sold under the brand name Amondys 45, is an antisense oligonucleotide medication used for the treatment of Duchenne muscular dystrophy (DMD) in people who have a confirmed mutation of the dystrophin gene that is amenable to exon 45 skipping. It is an antisense oligonucleotide of phosphorodiamidate …

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Viltolarsen

CAS NO.: 2055732-84-6Synonyms: NCNP-01Molecular Formula: C244H381N113O88P20Molecular Weight:6924.910 Application: Viltolarsen, sold under the brand name Viltepso, is a medication used for the treatment of Duchenne muscular dystrophy (DMD). Viltolarsen is a Morpholino antisense oligonucleotide. Any product involved in patent will be used for research purposes only.