Product
CAS NO.: 1420706-45-1Synonyms: ALN-18328Molecular Formula: C412H520N148O290P40Molecular Weight: N/A Application: Patisiran is a medication used for the treatment of polyneuropathy in people with hereditary transthyretin-mediated amyloidosis. It is a gene silencing drug that interferes with the production of an abnormal form of transthyretin. Any product involved in patent will be used for research purposes only.
CAS NO.: 1639325-43-1Synonyms: ALN-AS1Molecular Formula: C78H139N11O30Molecular Weight: 1709.968872 Da Application: Givosiran is indicated for the treatment of adults with acute hepatic porphyria, a genetic disorder resulting in the buildup of toxic porphyrin molecules which are formed during the production of heme (which helps bind oxygen in the blood). Any product involved in patent will be …
CAS NO.: 1834612-06-4Synonyms: N/AMolecular Formula: N/AMolecular Weight: N/A Application: Lumasiran sodium is an investigational RNA interference (RNAi) therapeutic agent, reduces hepatic oxalate production by targeting glycolate oxidase. Lumasiran sodium reduces urinary oxalate excretion, the cause of progressive kidney failure in primary hyperoxaluria type 1 (PH1). Any product involved in patent will be used for research …
CAS NO.: 1639324-58-5Synonyms: ALN-PCSsc: InclisiranMolecular Formula: C529H664F12N176O316P43S6Molecular Weight: N/A Application: Inclisiran sodium is a double-stranded small interfering RNA (siRNA) molecule that inhibits the transcription of PCSK-9. Inclisiran can be used for hyperlipidemia and cardiovascular disease (CVD) research. Any product involved in patent will be used for research purposes only.
CAS NO.: 1867157-35-4Synonyms: ALN-TTRsc02Molecular Formula: N/AMolecular Weight：16345 Application: Vutrisiran is a liver-directed, investigational, small interfering ribonucleic acid (siRNA) agent. Vutrisiran can be used for transthyretin (TTR)-mediated amyloidosis research. Any product involved in patent will be used for research purposes only.
CAS NO.: 1173755-55-9Synonyms: AVI-4658Molecular Formula: C364H569N177O122P30Molecular Weight：10305.74000 Application: Eteplirsen is a medication to treat, but not cure, some types of Duchenne muscular dystrophy (DMD), caused by a specific mutation. Eteplirsen only targets specific mutations and can be used to treat about 14% of DMD cases.Eteplirsen is a form of antisense therapy. Any product involved in …
CAS NO.: 1258984-36-9Synonyms: Nusinersen USP/EP/BPMolecular Formula: C234H340N61O128P17S17Molecular Weight：7127.194237 Application: Nusinersen, marketed as Spinraza, is a medication used in treating spinal muscular atrophy (SMA), a rare neuromuscular disorder. In December 2016, it became the first approved drug used in treating this disorder. Any product involved in patent will be used for research purposes only.
CAS NO.: 1432726-13-0Synonyms: ISIS-420915 sodiumMolecular Formula: C230H299N69Na19O121P19S19Molecular Weight：7601 Application: Any product involved in patent will be used for research purposes only.
CAS NO.: 915430-78-3 / 1573402-50-22 (sodium salt)Synonyms: ISIS 304801Molecular Formula: C230H320N63O125P19S19Molecular Weight：7165.05 Application: Volanesorsen, sold under the brand name Waylivra, is a triglyceride-reducing drug. It is a second-generation 2′-O-methoxyethyl (2′-MOE) chimeric antisense therapeutic oligonucleotide (ASO) that targets the messenger RNA for apolipoprotein C3 (apo-CIII). Any product involved in patent will be used for research purposes …
CAS NO.: 1422959-91-8Synonyms: SRP-4053Molecular Formula: C305H481N138O112P25Molecular Weight：8647.401 Application: Golodirsen, sold under the brand name Vyondys 53, is a medication used for the treatment of Duchenne muscular dystrophy (DMD). It is an antisense oligonucleotide drug of phosphorodiamidate morpholino oligomer (PMO) chemistry. Any product involved in patent will be used for research purposes only.
