{"id":264,"date":"2022-04-12T15:14:38","date_gmt":"2022-04-12T07:14:38","guid":{"rendered":"http:\/\/nugene.com.cn\/cn\/?p=264"},"modified":"2022-04-12T15:15:07","modified_gmt":"2022-04-12T07:15:07","slug":"%e5%bf%ab%e8%ae%af-%e5%8f%a3%e6%9c%8dmrna%e7%96%ab%e8%8b%97","status":"publish","type":"post","link":"https:\/\/nugene.com.cn\/cn\/index.php\/%e5%bf%ab%e8%ae%af-%e5%8f%a3%e6%9c%8dmrna%e7%96%ab%e8%8b%97\/","title":{"rendered":"\u5feb\u8baf-\u53e3\u670dmRNA\u75ab\u82d7"},"content":{"rendered":"\n<p>\u00a0       \u8fd1\u65e5BioNTech\u53d1\u5e03\uff0c\u516c\u53f8 \u4e0eMatinas Biopharma \u6b63\u5728\u534f\u540c\u5408\u4f5c\u63a2\u7d22\u65b0\u7684mRNA\u914d\u65b9\uff0c\u5176\u4e2d\u5305\u62ec\u53e3\u670d\u75ab\u82d7\u3002Matinas \u662f\u4e00\u5bb6\u5e74\u8f7b\u7684\u4e34\u5e8a\u9636\u6bb5\u751f\u7269\u5236\u836f\u516c\u53f8\uff0c\u603b\u90e8\u4f4d\u4e8eBedminster, New Jersey\u3002\u81ea 2013 \u5e74\u5f00\u59cb\u8fd0\u8425\u4ee5\u6765\uff0c\u8be5\u4f01\u4e1a\u4e00\u76f4\u81f4\u529b\u4e8e\u5f00\u53d1\u65b0\u9896\u3001\u6539\u53d8\u751f\u6d3b\u7684\u533b\u836f\u4ea7\u54c1\u3002<\/p>\n\n\n\n<p>\u00a0 \u00a0    \u9ebb\u7701\u7406\u5de5\u5b66\u9662Giovanni Traverso \u548cRobert Langer \u53d1\u8868\u6587\u7ae0\uff0c\u62a5\u9053\u4e86\u53e3\u670dmRNA\u75ab\u82d7\u7684\u53e3\u670d\u9012\u9001\u7cfb\u7edf\u3002Traverso \u548c Langer \u7684\u7814\u7a76\u5185\u5bb9\u4e4b\u4e00\uff0c\u4e00\u76f4\u5728\u5bfb\u627e\u6709\u6548\u548c\u5b89\u5168\u5730\u5411\u80c3\u80a0\u9053\u63d0\u4f9b\u6cbb\u7597\u836f\u7269\u7684\u65b0\u65b9\u6cd5\uff0c\u7279\u522b\u5173\u6ce8\u76ee\u524d\u901a\u8fc7\u6ce8\u5c04\u7ed9\u836f\u7684\u5927\u578b\u86cb\u767d\u8d28\u6cbb\u7597\u836f\u7269\u3002<\/p>\n\n\n\n<p>\u00a0      2021 \u5e74\uff0cTraverso \u548c Langer\u8bc1\u660e\u8be5\u80f6\u56ca\u53ef\u7528\u4e8e\u5728\u732a\u4f53\u5185\u8f93\u9001\u5355\u514b\u9686\u6297\u4f53\uff08\u6db2\u4f53\u5f62\u5f0f\uff09\u3002\u7136\u540e\uff0c\u4ed6\u4eec\u5c06\u76ee\u5149\u6295\u5411\u4e86\u63d0\u4f9b\u5927\u5206\u5b50\u7684\u6838\u9178\uff0c\u8fd9\u4e9b\u6838\u9178\u4e0e\u5355\u514b\u9686\u6297\u4f53\u548c\u80f0\u5c9b\u7d20\u4e00\u6837\u3002<\/p>\n\n\n\n<p>        mRNA\u88ab\u7eb3\u7c73\u805a\u5408\u7269\u4fdd\u62a4\uff0c\u8fdb\u5165\u732a\u7684\u80c3\u3002\u5e26\u7535\u7684\u805a\u5408\u7269\u914d\u5408mRNA\u4fc3\u4f7fmRNA\u5206\u5b50\u8fdb\u5165\u80c3\u7ec6\u80de\uff0c\u4ece\u800c\u5f00\u59cb\u86cb\u767d\u8868\u8fbe\u3002\u8be5\u805a\u5408\u7269\u7531poly(beta-amino esters)\u5236\u5907\uff0c\u5b9e\u9a8c\u8bc1\u660e\u53ef\u4ee5\u6709\u6548\u4fdd\u62a4\u6838\u9178\u5206\u5b50\u3002<\/p>\n\n\n\n<figure class=\"wp-block-embed\"><div class=\"wp-block-embed__wrapper\">\nhttps:\/\/mp.weixin.qq.com\/s?__biz=MzkwNTMxOTAyNQ==&#038;mid=2247483805&#038;idx=1&#038;sn=285b30b6f3570ea4aff6d886e59b252c&#038;chksm=c0f8c683f78f4f958e5c9f84a83e93fc6eb52323d5a9d9ba51f99934b9a1ce13e4328f53d8dc&#038;token=184647365&#038;lang=zh_CN#rd\n<\/div><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>  \u8fd1\u65e5BioNTech\u900f\u9732\u5f00\u542f\u7814\u7a76\u53e3\u670dmRNA<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[12],"tags":[],"class_list":["post-264","post","type-post","status-publish","format-standard","hentry","category-mrna"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>\u5feb\u8baf-\u53e3\u670dmRNA\u75ab\u82d7 - \u6838\u82af\u751f\u7269\u533b\u836f<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/nugene.com.cn\/cn\/index.php\/\u5feb\u8baf-\u53e3\u670dmrna\u75ab\u82d7\/\" \/>\n<meta property=\"og:locale\" content=\"zh_CN\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u5feb\u8baf-\u53e3\u670dmRNA\u75ab\u82d7 - \u6838\u82af\u751f\u7269\u533b\u836f\" \/>\n<meta property=\"og:description\" content=\"\u8fd1\u65e5BioNTech\u900f\u9732\u5f00\u542f\u7814\u7a76\u53e3\u670dmRNA\" \/>\n<meta property=\"og:url\" content=\"https:\/\/nugene.com.cn\/cn\/index.php\/\u5feb\u8baf-\u53e3\u670dmrna\u75ab\u82d7\/\" \/>\n<meta property=\"og:site_name\" content=\"\u6838\u82af\u751f\u7269\u533b\u836f\" \/>\n<meta property=\"article:published_time\" content=\"2022-04-12T07:14:38+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2022-04-12T07:15:07+00:00\" \/>\n<meta name=\"author\" content=\"Nugene\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"\u4f5c\u8005\" \/>\n\t<meta name=\"twitter:data1\" content=\"Nugene\" \/>\n\t<meta name=\"twitter:label2\" content=\"\u9884\u8ba1\u9605\u8bfb\u65f6\u95f4\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 \u5206\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/nugene.com.cn\/cn\/index.php\/%e5%bf%ab%e8%ae%af-%e5%8f%a3%e6%9c%8dmrna%e7%96%ab%e8%8b%97\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/nugene.com.cn\/cn\/index.php\/%e5%bf%ab%e8%ae%af-%e5%8f%a3%e6%9c%8dmrna%e7%96%ab%e8%8b%97\/\"},\"author\":{\"name\":\"Nugene\",\"@id\":\"https:\/\/nugene.com.cn\/cn\/#\/schema\/person\/2b56c7b86acf3e5a0d9995a878571b24\"},\"headline\":\"\u5feb\u8baf-\u53e3\u670dmRNA\u75ab\u82d7\",\"datePublished\":\"2022-04-12T07:14:38+00:00\",\"dateModified\":\"2022-04-12T07:15:07+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/nugene.com.cn\/cn\/index.php\/%e5%bf%ab%e8%ae%af-%e5%8f%a3%e6%9c%8dmrna%e7%96%ab%e8%8b%97\/\"},\"wordCount\":82,\"publisher\":{\"@id\":\"https:\/\/nugene.com.cn\/cn\/#organization\"},\"articleSection\":[\"mRNA\"],\"inLanguage\":\"zh-Hans\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/nugene.com.cn\/cn\/index.php\/%e5%bf%ab%e8%ae%af-%e5%8f%a3%e6%9c%8dmrna%e7%96%ab%e8%8b%97\/\",\"url\":\"https:\/\/nugene.com.cn\/cn\/index.php\/%e5%bf%ab%e8%ae%af-%e5%8f%a3%e6%9c%8dmrna%e7%96%ab%e8%8b%97\/\",\"name\":\"\u5feb\u8baf-\u53e3\u670dmRNA\u75ab\u82d7 - \u6838\u82af\u751f\u7269\u533b\u836f\",\"isPartOf\":{\"@id\":\"https:\/\/nugene.com.cn\/cn\/#website\"},\"datePublished\":\"2022-04-12T07:14:38+00:00\",\"dateModified\":\"2022-04-12T07:15:07+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/nugene.com.cn\/cn\/index.php\/%e5%bf%ab%e8%ae%af-%e5%8f%a3%e6%9c%8dmrna%e7%96%ab%e8%8b%97\/#breadcrumb\"},\"inLanguage\":\"zh-Hans\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/nugene.com.cn\/cn\/index.php\/%e5%bf%ab%e8%ae%af-%e5%8f%a3%e6%9c%8dmrna%e7%96%ab%e8%8b%97\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/nugene.com.cn\/cn\/index.php\/%e5%bf%ab%e8%ae%af-%e5%8f%a3%e6%9c%8dmrna%e7%96%ab%e8%8b%97\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"\u9996\u9875\",\"item\":\"https:\/\/nugene.com.cn\/cn\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"\u5feb\u8baf-\u53e3\u670dmRNA\u75ab\u82d7\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/nugene.com.cn\/cn\/#website\",\"url\":\"https:\/\/nugene.com.cn\/cn\/\",\"name\":\"\u6838\u82af\u751f\u7269\u533b\u836f\",\"description\":\"\u5408\u6210\u751f\u7269\u5b66\",\"publisher\":{\"@id\":\"https:\/\/nugene.com.cn\/cn\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/nugene.com.cn\/cn\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"zh-Hans\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/nugene.com.cn\/cn\/#organization\",\"name\":\"\u6838\u82af\u751f\u7269\u533b\u836f\u79d1\u6280\uff08\u676d\u5dde\uff09\u6709\u9650\u516c\u53f8\",\"url\":\"https:\/\/nugene.com.cn\/cn\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"zh-Hans\",\"@id\":\"https:\/\/nugene.com.cn\/cn\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/nugene.com.cn\/cn\/wp-content\/uploads\/2022\/02\/logo-nugene-cnweb-2.png\",\"contentUrl\":\"https:\/\/nugene.com.cn\/cn\/wp-content\/uploads\/2022\/02\/logo-nugene-cnweb-2.png\",\"width\":300,\"height\":90,\"caption\":\"\u6838\u82af\u751f\u7269\u533b\u836f\u79d1\u6280\uff08\u676d\u5dde\uff09\u6709\u9650\u516c\u53f8\"},\"image\":{\"@id\":\"https:\/\/nugene.com.cn\/cn\/#\/schema\/logo\/image\/\"}},{\"@type\":\"Person\",\"@id\":\"https:\/\/nugene.com.cn\/cn\/#\/schema\/person\/2b56c7b86acf3e5a0d9995a878571b24\",\"name\":\"Nugene\",\"sameAs\":[\"http:\/\/nugene.com.cn\/cn\"]}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"\u5feb\u8baf-\u53e3\u670dmRNA\u75ab\u82d7 - \u6838\u82af\u751f\u7269\u533b\u836f","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/nugene.com.cn\/cn\/index.php\/\u5feb\u8baf-\u53e3\u670dmrna\u75ab\u82d7\/","og_locale":"zh_CN","og_type":"article","og_title":"\u5feb\u8baf-\u53e3\u670dmRNA\u75ab\u82d7 - \u6838\u82af\u751f\u7269\u533b\u836f","og_description":"\u8fd1\u65e5BioNTech\u900f\u9732\u5f00\u542f\u7814\u7a76\u53e3\u670dmRNA","og_url":"https:\/\/nugene.com.cn\/cn\/index.php\/\u5feb\u8baf-\u53e3\u670dmrna\u75ab\u82d7\/","og_site_name":"\u6838\u82af\u751f\u7269\u533b\u836f","article_published_time":"2022-04-12T07:14:38+00:00","article_modified_time":"2022-04-12T07:15:07+00:00","author":"Nugene","twitter_card":"summary_large_image","twitter_misc":{"\u4f5c\u8005":"Nugene","\u9884\u8ba1\u9605\u8bfb\u65f6\u95f4":"1 \u5206"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/nugene.com.cn\/cn\/index.php\/%e5%bf%ab%e8%ae%af-%e5%8f%a3%e6%9c%8dmrna%e7%96%ab%e8%8b%97\/#article","isPartOf":{"@id":"https:\/\/nugene.com.cn\/cn\/index.php\/%e5%bf%ab%e8%ae%af-%e5%8f%a3%e6%9c%8dmrna%e7%96%ab%e8%8b%97\/"},"author":{"name":"Nugene","@id":"https:\/\/nugene.com.cn\/cn\/#\/schema\/person\/2b56c7b86acf3e5a0d9995a878571b24"},"headline":"\u5feb\u8baf-\u53e3\u670dmRNA\u75ab\u82d7","datePublished":"2022-04-12T07:14:38+00:00","dateModified":"2022-04-12T07:15:07+00:00","mainEntityOfPage":{"@id":"https:\/\/nugene.com.cn\/cn\/index.php\/%e5%bf%ab%e8%ae%af-%e5%8f%a3%e6%9c%8dmrna%e7%96%ab%e8%8b%97\/"},"wordCount":82,"publisher":{"@id":"https:\/\/nugene.com.cn\/cn\/#organization"},"articleSection":["mRNA"],"inLanguage":"zh-Hans"},{"@type":"WebPage","@id":"https:\/\/nugene.com.cn\/cn\/index.php\/%e5%bf%ab%e8%ae%af-%e5%8f%a3%e6%9c%8dmrna%e7%96%ab%e8%8b%97\/","url":"https:\/\/nugene.com.cn\/cn\/index.php\/%e5%bf%ab%e8%ae%af-%e5%8f%a3%e6%9c%8dmrna%e7%96%ab%e8%8b%97\/","name":"\u5feb\u8baf-\u53e3\u670dmRNA\u75ab\u82d7 - \u6838\u82af\u751f\u7269\u533b\u836f","isPartOf":{"@id":"https:\/\/nugene.com.cn\/cn\/#website"},"datePublished":"2022-04-12T07:14:38+00:00","dateModified":"2022-04-12T07:15:07+00:00","breadcrumb":{"@id":"https:\/\/nugene.com.cn\/cn\/index.php\/%e5%bf%ab%e8%ae%af-%e5%8f%a3%e6%9c%8dmrna%e7%96%ab%e8%8b%97\/#breadcrumb"},"inLanguage":"zh-Hans","potentialAction":[{"@type":"ReadAction","target":["https:\/\/nugene.com.cn\/cn\/index.php\/%e5%bf%ab%e8%ae%af-%e5%8f%a3%e6%9c%8dmrna%e7%96%ab%e8%8b%97\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/nugene.com.cn\/cn\/index.php\/%e5%bf%ab%e8%ae%af-%e5%8f%a3%e6%9c%8dmrna%e7%96%ab%e8%8b%97\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"\u9996\u9875","item":"https:\/\/nugene.com.cn\/cn\/"},{"@type":"ListItem","position":2,"name":"\u5feb\u8baf-\u53e3\u670dmRNA\u75ab\u82d7"}]},{"@type":"WebSite","@id":"https:\/\/nugene.com.cn\/cn\/#website","url":"https:\/\/nugene.com.cn\/cn\/","name":"\u6838\u82af\u751f\u7269\u533b\u836f","description":"\u5408\u6210\u751f\u7269\u5b66","publisher":{"@id":"https:\/\/nugene.com.cn\/cn\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/nugene.com.cn\/cn\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"zh-Hans"},{"@type":"Organization","@id":"https:\/\/nugene.com.cn\/cn\/#organization","name":"\u6838\u82af\u751f\u7269\u533b\u836f\u79d1\u6280\uff08\u676d\u5dde\uff09\u6709\u9650\u516c\u53f8","url":"https:\/\/nugene.com.cn\/cn\/","logo":{"@type":"ImageObject","inLanguage":"zh-Hans","@id":"https:\/\/nugene.com.cn\/cn\/#\/schema\/logo\/image\/","url":"https:\/\/nugene.com.cn\/cn\/wp-content\/uploads\/2022\/02\/logo-nugene-cnweb-2.png","contentUrl":"https:\/\/nugene.com.cn\/cn\/wp-content\/uploads\/2022\/02\/logo-nugene-cnweb-2.png","width":300,"height":90,"caption":"\u6838\u82af\u751f\u7269\u533b\u836f\u79d1\u6280\uff08\u676d\u5dde\uff09\u6709\u9650\u516c\u53f8"},"image":{"@id":"https:\/\/nugene.com.cn\/cn\/#\/schema\/logo\/image\/"}},{"@type":"Person","@id":"https:\/\/nugene.com.cn\/cn\/#\/schema\/person\/2b56c7b86acf3e5a0d9995a878571b24","name":"Nugene","sameAs":["http:\/\/nugene.com.cn\/cn"]}]}},"_links":{"self":[{"href":"https:\/\/nugene.com.cn\/cn\/index.php\/wp-json\/wp\/v2\/posts\/264","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nugene.com.cn\/cn\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nugene.com.cn\/cn\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nugene.com.cn\/cn\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/nugene.com.cn\/cn\/index.php\/wp-json\/wp\/v2\/comments?post=264"}],"version-history":[{"count":3,"href":"https:\/\/nugene.com.cn\/cn\/index.php\/wp-json\/wp\/v2\/posts\/264\/revisions"}],"predecessor-version":[{"id":267,"href":"https:\/\/nugene.com.cn\/cn\/index.php\/wp-json\/wp\/v2\/posts\/264\/revisions\/267"}],"wp:attachment":[{"href":"https:\/\/nugene.com.cn\/cn\/index.php\/wp-json\/wp\/v2\/media?parent=264"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nugene.com.cn\/cn\/index.php\/wp-json\/wp\/v2\/categories?post=264"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nugene.com.cn\/cn\/index.php\/wp-json\/wp\/v2\/tags?post=264"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}