Nugene

TIDES US 2023

INDUSTRY’S LARGEST & MOST RENOWNED EVENT TO ACCELERATE YOUR THERAPEUTICS TO MARKET: LEADING STRATEGIES FOR EXPEDITING R&D AND IMPROVING CMC EFFICIENCY INDUSTRY-LEADING SPEAKERS SHARE CUTTING-EDGE SCIENCE AND PROGRESS Moderna, BioNTech, Ionis, Aro Biotherapeutics, Alnylam, Bicycle Therapeutics, Intellia will speak. San Diego, CA, USA May 7-10, 2023 Agenda Drug Delivery Innovations Explore new technologies and approaches …

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pseudouridine-5′-Triphosphate

Nugene Biopharm Science providepseudouridine-5′-Triphosphate solution 100mM Sodium and 200mM Tris for RNA synthesis, mRNA synthesis, IVT.Packing size: 1mL, 10mL, 20mL, 100mL, 1L, etc.GMP management as per API manufacturing, approved Chinese FDA. Molecular Formula: C9H15N2O15P3Molecular Mass: 484.144 InChIInChI=N/A InChIKeyInChIKey=VEWJOCYCKIZKKV-GBNDHIKLSA-N Other Names for this Substance Bioactivity: MODERNA THERAPEUTICS INC – US2021/38529, 2021, A1

Adenosine 5′-triphosphate

Nugene Biopharm Science provide Adenosine 5′-triphosphate solution 100mM Sodium and 200mM Tris for RNA synthesis, mRNA synthesis, IVT.Packing size: 1mL, 10mL, 20mL, 100mL, 1L, etc.GMP management as per API manufacturing, approved Chinese FDA. Molecular Formula: C10H16N5O13P3Molecular Mass: 507.18 InChIInChI=1S/C10H16N5O13P3/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1 InChIKeyInChIKey=ZKHQWZAMYRWXGA-KQYNXXCUSA-N SMILESO[C@H]1C@N=CN3)(OC@HO)(=O)O)(=O)O)[C@H]1O)[H] Canonical SMILESO=P(O)(O)OP(=O)(O)OP(=O)(O)OCC1OC(N2C=NC=3C(=NC=NC32)N)C(O)C1O Other Names for this SubstanceAdenosine 5′-(tetrahydrogen triphosphate)Adenosine 5′-triphosphateAdenosine triphosphateAdenosine 5′-triphosphoric acidAtipi

Chinese mRNA vaccine research and development company Suzhou Abogen Biosciences Co., Ltd. is raising approximately US$300 million.

People familiar with the matter said that relevant consultations are still in progress, and details such as the scale and timing of fundraising may be adjusted. A spokesperson for the SoftBank Vision Fund declined to comment, and representatives of Abogen and Mirae Asset did not immediately respond to requests for comment or were unable to …

Chinese mRNA vaccine research and development company Suzhou Abogen Biosciences Co., Ltd. is raising approximately US$300 million. Read More »

GMP site for the urgently needed supply of key raw materials in the mRNA industry chain

Nugene Biopharm Science (Hangzhou) Co., Ltd. is investing 200 million yuan to build a commercial production base and a research and development center, that can meet the urgently needed supply of key raw materials in the mRNA industry chain. The 6000 square meter research and development center has been completed, providing global mRNA customers with …

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Immorna announced the completion of a round A financing of more than RMB 100 million

“I think the research and development of innovative new drugs requires a long-term process. You can stand on the shoulders of giants to gain certain advantages, but it is impossible overnight. Investors choose Jiachen Xihai to value our stable construction and vision.” In early 2021, Jiachen Xihai announced the completion of a series A financing …

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Cordycepin

Cunningham et al. reported 3’-deoxyadenosine(Cordycepin) was first isolated from the culture filtrate of the medicinal fungus Cordyceps militaris in 1950.Herba Su has been identified as one of the important active ingredients of Cordyceps militaris.Cordycepin has a wide range of medical and health care values.Its medicine Physical activity includes anti-cancer, anti-metastasis, anti-tumor, anti-apoptosis, anti-inflammatory.Cordycepin can also …

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Lipid Nanoparticles for Therapeutic Delivery of GTI-2040

Mol Pharm . 2015 Jun 1;12(6):2010-8. doi: 10.1021/mp5008212. Epub 2015 Apr 28. D33-targeted lipid nanoparticles (aCD33LNs) were synthesized for delivery of GTI-2040, an antisense oligonucleotide (ASO) against the R2 subunit of ribonucleotide reductase, to acute myelogenous leukemia (AML). These LNs incorporated a deoxycholate-polyethylenimine (DOC-PEI) conjugate, which has shown significant activity to facilitate oligonucleotide delivery. Anti-CD33 scFv (aCD33) was …

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IVT mRNA is formulated into lipid nanoparticle vaccines using a cell-free production pipeline

author: Namit Chaudhary , Drew Weissman and Kathryn A. Whitehead Over the past several decades, messenger RNA (mRNA) vaccines have progressed from a scepticism-inducing idea to clinical reality. In 2020, the COVID-19 pandemic catalysed the most rapid vaccine development in history, with mRNA vaccines at the forefront of those efforts.Although it is now clear that …

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